All About PrEP

Pre-Exposure Prophylaxis (PrEP) is a daily pill that can help you stay HIV-negative. The medicines in PrEP can protect you before you might be exposed to HIV.

PrEP Resources for Patients

What is PrEP
Where To Get PrEP
The Basics
Patient Resources
Provider Resources
Find a PrEP Provider
PrEP Hotline

Where can I get PrEP in New Hampshire?

The New Hampshire HIV Planning Group is in the process of rolling out Granite State PrEP Connect, your connection to all things PrEP in New Hampshire. Please visit our website for more information and the most up-to-date listing of PrEP providers in the state.

You may also contact the statewide PrEP navigator by calling or texting the Granite State PrEP Line at 508-686-PrEP (7737), or by emailing

Additional resources and guidelines for providers can be found here.

More information on free, confidential PrEP navigation services can be found here.



Daily PrEP to Prevent HIV: The Basics

Consider PrEP

PrEP is for HIV-negative people who are at risk of being exposed to HIV through sex or injecting drugs and who are ready to take a daily pill.

Talk to Your Doctor

You need to speak with a doctor or nurse before you start using PrEP. Your doctor or nurse can help you decide if PrEP is right for you.

Take PrEP Every Day

PrEP is taken daily in pill form. Do not skip a dose. PrEP works much better at stopping HIV if you take it every day.

Use Condoms

Even if you take PrEP daily, condoms give you additional protection against HIV, other sexually transmitted infections and unintended pregnancy. PrEP does not protect you from sexually transmitted diseases other than HIV infection.

Know the Common Side Effects

PrEP can have mild side effects, like stomach pain, weight loss and headaches, especially at the beginning of treatment. PrEP may not be right for everyone. Talk to your doctor.

Find Out about Paying for PrEP

Many insurance plans including Medicaid cover PrEP. Assistance may be available if you are uninsured.

Frequently Asked Questions About PrEP

How does PrEP stop HIV?

PrEP contains the same medicines that people with HIV use to stay healthy. If you are exposed to HIV, these medicines can stop the virus from multiplying and spreading throughout your body. PrEP only works if you have enough medicine in your body, so you need to take PrEP every day.

Should I consider taking PrEP?

PrEP is for people who are HIV-negative, have a high risk of being exposed to HIV through sex or drug injection, and are ready to take a daily pill. Studies have shown that PrEP works for sexually-active gay and bisexual men, heterosexual women and men, and injection drug users; and is also likely to benefit transgender women. PrEP can help protect anyone whose partner has HIV.

How do I take PrEP?

PrEP is prescribed by a doctor or nurse. You should take PrEP exactly as prescribed. With PrEP, you take a pill once a day, even on the days you don’t have sex or inject drugs. View the User’s Guide to PrEP [Español] (PDF) to learn what to expect when taking PrEP. The only medication currently approved for PrEP is Truvada®, a combination pill that contains two different medicines: emtricitabine (Emtriva®) and tenofovir (Viread®). PrEP only works if you are HIV-negative.

  • Before you start PrEP, you take an HIV test to make sure that you do not have HIV. You also have a check-up to make sure your kidneys and liver are healthy.
  • While you are on PrEP, your doctor or nurse will test you regularly for HIV and other sexually transmitted infections. They will also ask you about your HIV risk and whether you are taking PrEP every day.

PrEP can help you stay HIV-negative when your risk of HIV exposure is high. You may decide to stop taking this medication if your risk changes. But do not stop taking PrEP without first talking to your doctor. Also, tell your doctor if you are thinking about becoming pregnant or if you become pregnant while on PrEP.

PrEP is safe? What are the side effects?

PrEP is safe. The pill used for PrEP, Truvada®, has been used to treat people with HIV since 2004. PrEP can cause mild side effects, including upset stomach, headaches and weight loss, especially at the beginning of treatment. Rare side effects include kidney or bone problems. Your doctor or nurse can help if side effects are bothering you.

How well does PrEP work?

PrEP is not 100% effective. You can still get HIV, especially if you do not have not enough medicine in your body. In different studies, people taking PrEP were 44% to 75% less likely to get HIV than comparison groups, and people who took PrEP consistently were up to 92% less likely to get HIV.

Can I take PrEP only on the days when I have sex?

No. You must take PrEP every day to keep enough medicine in your body to protect you from HIV.

If I take PrEP, do I still have to use condoms?

PrEP does not provide 100% protection against HIV. Condoms provide additional protection against HIV, even while you take PrEP. Condoms also protect against other sexually transmitted infections and prevent unintended pregnancy. For greater protection against HIV, combine PrEP with other ways to reduce HIV risk.

  • Use condoms.
  • Choose kinds of sex with less risk of spreading HIV, like oral sex.
  • Get tested with your partners for HIV and other sexually transmitted infections.
  • Encourage partners living with HIV to take their medications every day.
  • If alcohol or drugs are a problem, get help.
  • If you inject drugs, always use a clean needle and syringes.
How do I talk with my provider about PrEP?

PrEP is a new medical option to help prevent HIV infection. Because it is a medical intervention, people interested in having PrEP prescribed must have a conversation with their medical provider or with a medical provider at a PrEP clinic. The following link offers suggestion about how to begin that conversation.

How do I pay for PrEP?

Since PrEP is a medical intervention rewuiring a prescription, most insurances will pqy for PrEP. Your PrEP provider may know of additional resources to help. the following is a link to Gilead’s application for payment assistance for Truvada for Prep.

Helpful Apps

Every Dose Every Day: PrEP Adherence App

Every Dose Every Day

Additional PrEP Patient Resources

PEP & PrEP: New Ways to Prevent HIV

PrEP Self-Assessment Card:

PrEP Watch: Clearinghouse for PrEP Resources

What Is PrEP?

PrEP: My Experience

The Body: The Complete HIV/AIDS Resource

PrEP Informational Video       



Helpful Apps

Every Dose Every Day: PrEP Adherence App

Every Dose Every Day

PrEP Resources for Providers

Pre Exposure Prophylaxis (PrEP)

Pre-exposure prophylaxis, or PrEP, is a way for people who do not have HIV but who are at substantial risk of getting it to prevent HIV infection by taking a pill every day.  The pill (brand name Truvada) contains two medicines (tenofovir and emtricitabine) that are used in combination with other medicines to treat HIV.

The following resources have been gathered from the Centers for Disease Control & Prevention and the New York City PrEP/PEP website.  All resources have been reviewed by the NH HIV Planning Group’s PrEP Workgroup and have been determined to be helpful resources for any physician electing to provide PrEP for his or her patients requesting the treatment.

PrEP Provider Facts

Prep Provider Facts (PDF)

Taking a Sexual History (Card)

STD Screening and Vaccination Guideline Table

CDC 2015 STD Treatment Guidelines

NYC STD Treatment Guidelines Table

PrEP Medication Assistance Application

PrEP Billing Codes

How to Order Patient Materials

HIV Surveillance Report

HIV & STD Publications

Current PrEP Providers in New Hampshire

It is always best to talk with your primary care physician about all your medical/health issues and concerns including PrEP. If your physician is not familiar with PrEP, there are provider resources that can help. If this is not an option for you, there are currently eleven PrEP clinics in NH and VT for NH residents:   

Equality Health Center – Concord  38 South Main Street,  Concord, NH // Toll free 855-502-3858 Local calls 603-225-2739                                      

Joan G. Lovering Health Center  559 Portsmouth Ave,  Greenland, NH // Toll Free: 1-877-436-7588 Phone: 603-436-7588

Dartmouth Hitchcock HIV Program  1 Medical Center Drive Lebanon, NH 03756 // Phone: 603-650-6060

Dick’s House   7 Rope Ferry Rd. Hanover, NH 03755 // Phone: 603-646-9400 *student health for Dartmouth College students only

Planned Parenthood – Manchester  24 Pennacook Street,  Manchester, NH 03104 // Phone: 603-669-7321

Planned Parenthood – Derry  4 Birch St. Derry, NH 03038 // Phone: 603-434-1354

Planned Parenthood – Claremont  136 Pleasant St Claremont, NH 03743 // Phone: 603-542-4568

Planned Parenthood – Keene  8 Middle St. Keene, NH 03431 // Phone: 603-352-6898

Planned Parenthood – Exeter  108 High St. Exeter, NH 03833 // Phone: 603-772-9315

Planned Parenthood – White River Junction  79 S Main St. White River Junction, VT 05001 // Phone: 802-281-6056

Planned Parenthood – St. Johnsbury  501 Portland St. St. Johnsbury, VT 05819 // Phone: 802-751-7821

Granite State PrEP Hotline: 508-686-PrEP (7737)

Call or text seven days a week for questions relating to all things PrEP, HIV testing, and sexual health.

More information available at

CDC PrEP Hotline: 855 HIV PrEP (855 448-7737)